Mansoureh Khojasteh, the wife of Iran’s late Supreme Leader Ali Khamenei, has died after reportedly suffering injuries in recent strikes, Iranian state media said.
The announcement comes amid intensifying tensions following Khamenei’s death in coordinated US-Israeli attacks targeting sites in and around Tehran. According to state outlets, Khojasteh was wounded during the same series of strikes and later died from her injuries.
Khojasteh, 78, was Khamenei’s only wife. The couple married in 1964.
Khamenei was killed in the initial phase of the operation, which officials from the United States and Israel described as targeting key military and security infrastructure. Confirmation of his death by Iranian media followed a public statement by US President Donald Trump, who characterised the strike as part of a broader campaign.
Reports have also indicated that several members of Khamenei’s family — including his daughter, son-in-law and granddaughter — were killed in the same attacks. A member of Tehran’s city council, cited by Reuters through the Young Journalists Club, had earlier confirmed fatalities within the Supreme Leader’s extended family.
The deaths within Khamenei’s immediate family are expected to heighten internal pressures and further strain regional stability. Iranian officials have warned that attacks on the country will prompt retaliation.
The conflict has widened significantly, with exchanges entering a third day. The Iranian Red Crescent Society reported that at least 555 people have been killed across Iran. Israeli strikes have also expanded into southern Lebanon, where dozens of casualties have been reported.
In response to the joint strikes, Iran has launched drones and missiles toward Israel and Gulf locations hosting US forces. The United States Central Command said four American service members have been killed in the exchanges.
Israel has continued operations in Tehran and broadened its campaign into Lebanon, as Hezbollah fired rockets and drones toward Israeli territory. Israeli officials have warned of prolonged combat.
The crisis is also affecting global trade and travel. Some shipping companies have halted transit through the Suez Canal, while airspace closures across several Middle Eastern countries have disrupted flights. Concerns are also growing about potential interruptions to oil shipments through the Strait of Hormuz, a key route for global crude supplies.
On Monday, the Pentagon reiterated that the campaign against Iran would not become an open-ended conflict like Iraq, stating that US forces were conducting strikes in a focused and overwhelming manner.
